Monday, January 30, 2017

Thinking about ordering an AuDNA test? What can you do with it?

If you have been considering buying a DNA test to use for genealogy, here are a few things to consider.

First, have you found most of your ancestors through old-fashioned research? If not, DNA might not yield you much information. That said, even if you are adopted and don't know much about your birth lineage, with a lot of work, you can make some matches, and learn more. However, the more you know, the better you will be able to use what you learn from DNA.

Next, what sort of test will help you learn the most? If you want to learn more about your "surname line," that of your birth father, his father, and on up -- then you want a yDNA test, and FamilyTreeDNA is the only place to get it. You will need a male of this line to do the test; daughters do not inherit their father's yDNA. Of course, you can test a male in *each* of your surname lines, but again, this only tells you about the male lines. You will want to test as many markers as you can afford; at least 67 markers if possible.

If you want to learn about all your relatives, then you want an autosomal DNA (auDNA) test from Ancestry, FamilyTreeDNA, 23andMe, or the new one on the block, MyHeritage. If you are already an Ancestry member and don't care about what your DNA says about your health, Ancestry is the right choice. (They have removed some of the genes which have health implications from their testing.)

If you are already testing at FTdna for yDNA or mtDNA, then "Family Finder" is your best choice.

If you care a bit about genealogy, but really want to know what your DNA says about your health, then 23andMe is the most popular. However, I think that their genealogy "helps" are the opposite these days, the health information seems over-simplified, and the high cost of the kits leads me to advise against using 23andMe. And yes, I tested there! At least it used to be less expensive. I found out more about health effects from Promethease than I have from 23&me.

The new choice, MyHeritage is my current favorite, since it is inexpensive ($75) and you can nearly always see a family tree, which is a problem with the others, even sometimes Ancestry. They use FTdna to do the processing, so they'll be top-notch results.

The final test one can do is mitochondrial DNA, which we all inherit from our mothers. Taking this test follows your mother's mother's mother's line far into the past. People have gotten matches from doing this test, but since mDNA is so stable, it is more about your deep past than present-day cousins. Again, FTdna is the only major company doing this testing.

No matter what company you choose, get your "raw results." If you do an auDNA test, you can
upload to GEDMatch if you wish. GEDMatch offers a lot of interesting stuff, such as comparisons with ancient DNA on file, possible localities where your ancestors lived, and the ability to partially
reconstruct the genome of a missing relative, given enough other testing. I do not yet know whether or not the MyHeritage kits will offer me the opportunity to download the raw data. I very much hope
so, and that GEDMatch will find a way to let me upload this data easily.

I think it is also important, if you use Wikitree (and you should) to link in your various tests there too. You do not upload results; simply put in your tests and also report matches among your relatives you have already made. This solidifies the results for cousins who tie into your tree, and may induce them to test too! They make it very easy. Wikitree is all about collaboration, and is the main reason I love this site!

If you do Y or Mt DNA at FTdna, they make it easy for you to upload to Mitosearch, which allows people who have tested elsewhere to upload their raw data. I've done it, although without any hits I've not seen on FTdna already. They have a similar free service for yDNA called ysearch. One can upload a gedcom, and I think it is worth doing so, if you have done the tests.

For health effects, there is a site called Promethease, which gives you an amazing amount of information for $5.

Other options: http://regenerationnet.com/4-tools-analyze-personal-dna describes four of the best, including GEDMatch and Promethease.

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